well, there are some major changes
but honestly if you have a reseller account it is a lot better for resellers
check out some of the features, it has an integrated payment system and some other neat tools, I might be actually offering both in the near future, or brand a daughter company.
moving over from cpanel looks easy. I read osme of the forum posts and it looks like the staff of h-sphere has made some helpful tools. Your host will have more information on this. The only problem i could see for you is if you have customers wheather they would mind the change. if your account is just reseller to have the features and such, well if all up to if you like it better then cpanel and don't want to find a new host.